You will go bankrupt when your brew cash is below zero immediately after making a batch of beer.

In bankruptcy all of your remaining brewing supplies are sold (liquidated) at rock bottom prices to pay off your debt. Any remaining funds are deposited back into your account for use on future batches. Ten percent of your last batch of beers are also taken away to pay the banker's liquidation fees.

Tip: A common early mistake is to buy too many supplies and not leave enough funds in your account to cover heating and miscellaneous costs for your next batch. Always make sure you have enough brew cash on hand before brewing a new batch. You may have to wait for beer sales to catch up but doing so will save you money in the long run. Bankruptcy is very expensive and should be avoided.

Another tip... avoid paying full price for brewing materials, order them in advance and wait for players to farm materials and send them to you. You can farm your own materials without any penalty also if you are willing to take the time. If you start brewing beer and don't have sufficient supplies on hand then they will be rushed to you so you can continue brewing but at exorbitant prices. If you pay full price for materials and later go bankrupt then you will lose a great deal of money when those materials are liquidated and you may not be able to save your brewery.

Help! I have no more money to brew and I am sinking deeper in debt.

This game can be rough on the beginning player, if you find yourself in a sitution where you bank account is in the red and you can't pre-order supplies and your next batch will barely get you out of the hole well don't despair. I have bailed out many a new player who didn't realize the need to conserve their early brew cash and I will take care of you too, just speak up. I think every new player who wants to pull themselves back up by their bootstraps should be given a second chance, so if I see you struggling with low funds at the start of the game I may intervene and get you started again.